Encoded by the TCR Vα24-Jα18 germline configuration, Vα24-JαQ is expressed on a subset of NKT cells, namely invariant NKT (iNKT). Vα24-JαQ TCR interacts with the glycolipid loaded MHC class 1b molecule CD1d, inducing activation and subsequent cytokine production. iNKT cells have been implicated in immune regulation, tumor surveillance, and host response to pathogens. While iNKT cells occur at low frequency in the blood, assorted chemokines contribute to their tissue homing potential.

Codice: AN00568D_20Tests | Marca: Elabscience | Confezionamento: 20Tests

Specie: HumanIsotipo: Mouse IgG1Clone: 6B11

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Codice: AN00568D_20Tests
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: 5 μL/Test
Link: https://www.elabscience.com/p-pe_anti_human_tcr_vα24_jα18_antibody[6b11]-an00568d
Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Isotipo: Mouse IgG1
Clonalità: Monoclonal
Clone: 6B11
Applicazione: FCM
Simbolo target: TCR Vα24-Jα18;TCR Vα24-JαQ;invariant NKT cell;iNKT

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