NK-1.1 surface antigen, also known as CD161b/CD161c and Ly-55, is encoded by the NKR-P1B/NKR-P1C gene. It is expressed on NK cells and NK-T cells in some mouse strains, including C57BL/6, FVB/N, and NZB, but not AKR, BALB/c, CBA/J, C3H, DBA/1, DBA/2, NOD, SJL, and 129. Expression of NKR-P1C antigen has been correlated with lysis of tumor cells in vitro and rejection of bone marrow allografts in vivo. NK-1.1 has also been shown to play a role in NK cell activation, IFN-γ production, and cytotoxic granule release. NK-1.1 and DX5 are commonly used as mouse NK cell markers.

Dettagli prodotto

• Codice: E-AB-F0987UL_25μg
• Marca: Elabscience
• Specie target: Mouse
• Host: Mouse
• Concentrazione: 0.5 mg/mL
• Link: https://www.elabscience.com/p-elab_fluor®_488_anti_mouse_cd161/nk1.1_antibody[pk136]-e_ab_f0987ul
• Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
• Isotipo: Mouse IgG2a, κ
• Clonalità: Monoclonal
• Clone: PK136
• Applicazione: FCM
• Simbolo target: CD161 antigen-like family member C;CD161;NK1.1;CD161c;Killer cell lectin-like receptor subfamily B member 1C;Klrb1c;Ly-55c;NKR-P1 40;NKR-P1.9;NKR-P1C
• Area di ricerca: Immunology;Innate Immunity