CD86 is an 80 kD immunoglobulin superfamily member also known as B7-2, B70, and Ly-58. CD86 is expressed on activated B and T cells, macrophages, dendritic cells, and astrocytes. CD86, along with CD80, is a ligand of CD28 and CD152 (CTLA-4). CD86 is expressed earlier in the immune response than CD80. CD86 has also been shown to be involved in immunoglobulin class-switching and triggering of NK cell-mediated cytotoxicity. CD86 binds to CD28 to transduce co-stimulatory signals for T cell activation, proliferation, and cytokine production. CD86 can also bind to CD152, also known as CTLA-4, to deliver an inhibitory signal to T cells.

Codice: E-AB-F0994Q2_50Tests | Marca: Elabscience | Confezionamento: 50Tests

Specie: MouseIsotipo: Rat IgG2a, κClone: GL1

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Codice: E-AB-F0994Q2_50Tests
Marca: Elabscience
Specie target: Mouse
Host: Rat
Concentrazione: 5 μL/Test
Link: https://www.elabscience.com/p-elab_bright™_violet_421_anti_mouse_cd86_antibody[gl_1]-e_ab_f0994q2
Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Isotipo: Rat IgG2a, κ
Clonalità: Monoclonal
Clone: GL1
Applicazione: FCM
Simbolo target: T-lymphocyte activation antigen CD86;Cd86;Activation B7-2 antigen;Early T-cell costimulatory molecule 1;ETC-1

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