CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Codice: E-AB-F1075P_20Tests | Marca: Elabscience | Confezionamento: 20Tests

Specie: HumanIsotipo: Mouse IgG2b, κClone: IV-3

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Codice: E-AB-F1075P_20Tests
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: 5 μL/Test
Link: https://www.elabscience.com/p-pe/elab_fluor®_594_anti_human_cd32_antibody[iv_3]-e_ab_f1075p
Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Isotipo: Mouse IgG2b, κ
Clonalità: Monoclonal
Clone: IV-3
Applicazione: FCM
Simbolo target: IGFR2;CD32;CDw32;FCG2;FCGR2B;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;IgG Fc receptor II-b;Low affinity immunoglobulin gamma Fc region receptor II-b
Area di ricerca: Immunology;Innate Immunity

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