CD11b is a 170 kD glycoprotein also known as αM integrin, Mac-1 α subunit, Mol, CR3, and Ly-40. CD11b is a member of the integrin family, primarily expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b non-covalently associates with CD18 (β2 integrin) to form Mac-1. Mac-1 plays an important role in cell-cell interaction by binding its ligands ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4 (CD242), iC3b, and fibrinogen.

Dettagli prodotto

• Codice: E-AB-F1081Q_100Tests
• Marca: Elabscience
• Specie target: Human;Mouse
• Host: Rat
• Concentrazione: 5 μL/Test
• Link: https://www.elabscience.com/p-elab_fluor®_violet_450_anti_mouse/human_cd11b_antibody[m1/70]-e_ab_f1081q
• Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
• Isotipo: Rat IgG2b, κ
• Clonalità: Monoclonal
• Clone: M1/70
• Applicazione: FCM
• Simbolo target: CD11 antigen-like family member B;CD11b;CR-3 alpha chain;Integrin alpha-M;Itgam;Leukocyte adhesion receptor MO1
• Area di ricerca: Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity;Neuroscience;Neuroscience Cell Markers