CD27 is a 50-55 kD type I membrane protein also known as S152 and T14. It is a lymphocyte-specific member of the TNF-receptor superfamily. CD27 is expressed on medullary thymocytes, virtually all mature T cells, some B cells, and NK cells. CD27 binds to CD70 and plays an important role in costimulation of T cell activation, and regulation of B cell differentiation and proliferation. The cytoplasmic domains of CD27 have also been shown to interact with TRAF2 and TRAF5 to elicit NF-κB and SAPK/JNK activation.

Codice: E-AB-F1140J_100Tests | Marca: Elabscience | Confezionamento: 100Tests

Specie: HumanIsotipo: Mouse IgG1, κClone: O323

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Codice: E-AB-F1140J_100Tests
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: 5 μL/Test
Link: Apri link
Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Isotipo: Mouse IgG1, κ
Clonalità: Monoclonal
Clone: O323
Applicazione: FCM
Simbolo target: CD27L receptor;S152;T-cell activation antigen CD27;T14;TNFRSF7
Area di ricerca: Costimulatory Molecules;Immunology

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