CD11b is a 165-170 kD type I transmembrane glycoprotein also known as αMintegrin, Mac-1, CR3, and C3biR. CD11b non-covalently associates with integrin β2(CD18) and is expressed on granulocytes, monocytes/macrophages, dendritic cells, NK cells, and subsets of T and B cells. CD11b/CD18 is critical for the transendothelial migration of monocytes and neutrophils. It is also involved in granulocyte adhesion, phagocytosis, and neutrophil activation. CD11b/CD18 interacts with ICAM-1 (CD54), ICAM-2 (CD102), ICAM-4, CD14, CD23, heparin, iC3b, fibrinogen, and factor X.

Codice: E-AB-F1146H_100Tests | Marca: Elabscience | Confezionamento: 100Tests

Specie: HumanIsotipo: Mouse IgG1, κClone: ICRF44

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Codice: E-AB-F1146H_100Tests
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: 5 μL/Test
Link: Apri link
Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Isotipo: Mouse IgG1, κ
Clonalità: Monoclonal
Clone: ICRF44
Applicazione: FCM
Simbolo target: CD11 antigen-like family member B;CD11b;CR-3 alpha chain;Integrin alpha-M;Itgam;Leukocyte adhesion receptor MO1
Area di ricerca: Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity;Neuroscience;Neuroscience Cell Markers

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