CD117 is a 145 kD protein tyrosine kinase also known as c-Kit. It is a receptor for stem cell factor or c-Kit ligand. CD117 is expressed on pluripotent hematopoietic progenitor cells (approximately 1-4% bone marrow cells), mast cells, and acute myeloid leukemia cells (AML). CD117 binding of c-Kit ligand induces phosphorylation of CD117 and stimulates proliferation and survival of primitive hematopoietic stem cells as well as erythroid-committed and granulo-monocytic committed cells.

Codice: E-AB-F1150H_100Tests×2 | Marca: Elabscience | Confezionamento: 100Tests×2

Specie: HumanIsotipo: Mouse IgG1, κClone: 104D2

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Codice: E-AB-F1150H_100Tests×2
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: 5 μL/Test
Link: Apri link
Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Isotipo: Mouse IgG1, κ
Clonalità: Monoclonal
Clone: 104D2
Applicazione: FCM
Simbolo target: CD117;Kit;Mast/stem cell growth factor receptor Kit;Proto-oncogene c-Kit;SCFR;Tyrosine-protein kinase Kit;c-Kit
Area di ricerca: Immunology;Stem Cells

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