FcεRIα is a transmembrane protein belonging to the Ig superfamily. FcεRIα forms a tetrameric complex with one β and two γ-subunits. The FcεRI complex plays an important role in triggering IgE-mediated allergic reactions. It is abundantly expressed on mast and basophils and up-regulated by the presence of IgE. Following stimulation via FcεRIα, mast cells and basophils release bioactive chemical mediators such as histamine, resulting in the initiation of allergic reactions. Cross linking of the high-affinity receptor for IgE on tissue mast cells triggers immediate hypersensitivity with local symptoms. The MAR-1 monoclonal antibody reacts with the FcεRIα subunit.

Codice: E-AB-F1188C_100Tests | Marca: Elabscience | Confezionamento: 100Tests

Specie: MouseIsotipo: Armenian Hamster IgGClone: MAR-1

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Codice: E-AB-F1188C_100Tests
Marca: Elabscience
Specie target: Mouse
Host: Armenian Hamster
Concentrazione: 5 μL/Test
Link: https://www.elabscience.com/p-fitc_anti_mouse_fcεriα_antibody[mar_1]-e_ab_f1188c
Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
Isotipo: Armenian Hamster IgG
Clonalità: Monoclonal
Clone: MAR-1
Applicazione: FCM
Simbolo target: Fc-epsilon RI-alpha;FcERI;Fcer1a;High affinity immunoglobulin epsilon receptor subunit alpha
Area di ricerca: Immunology;Innate Immunity

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