CD95 is a 45 kD single chain type I glycoprotein also known as Fas, APO-1, and TNFRSF6. It is a member of the TNF receptor superfamily. CD95 is expressed on T and B lymphocytes, monocytes, neutrophils, and fibroblasts. CD95 expression is upregulated by activation. The extracellular region of CD95 binds to CD178 (Fas ligand). CD178 binding to CD95 induces apoptosis and has been shown to play a role in the maintenance of peripheral tolerance.

Dettagli prodotto

• Codice: E-AB-F1379L_20Tests
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Link: https://www.elabscience.com/p-elab_fluor®_488_anti_human_cd95/fas_antibody[hfe7a/apo]-e_ab_f1379l
• Stoccaggio: This product can be stored at 2-8°C for 12 months. Please protected from prolonged exposure to light and do not freeze.
• Isotipo: Mouse IgG2a, κ
• Clonalità: Recombinant
• Clone: HFE7A/APO
• Applicazione: FCM
• Simbolo target: APT1;Apo-1 antigen;FAS1;FASLG receptor;TNFRSF6;Fas
• Area di ricerca: Apoptosis/Tumor Suppressors/Cell Death;Cell Biology;Immunology;Neuroscience