CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression.

Codice: AN002860P_100mg | Marca: Elabscience | Confezionamento: 100mg

Specie: HumanIsotipo: Mouse IgG3, κClone: 5F7
Note

Recombinant Human CD52 protein

Dettagli prodotto
  • Codice: AN002860P_100mg
  • Marca: Elabscience
  • Specie target: Human
  • Host: Mouse
  • Concentrazione: ≥ 1 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
  • Isotipo: Mouse IgG3, κ
  • Clonalità: Monoclonal
  • Clone: 5F7
  • Applicazione: FCM
  • Simbolo target: CDW;Epididymal secretory protein E;Human epididymis-specific protein;CAMPATH;CAMPATH-1;CAMPATH-1 antigen;CD52 antigen;CD52 molecule;Epididymal secretory protein E5;HEL-S-171mP;Human epididymis-specific protein 5;CDW52;HE5;CD52; HE5
  • Area di ricerca: Immunology