CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Isotipo: Mouse IgG2a, κ
Clonalità: Monoclonal
Clone: 10E5-F0061
Applicazione: FCM
Simbolo target: HPA;PPP1R;ITGA2B;BDPLT16;BDPLT2;CD41;CD41B;GP2B;GPIIb;GT;GTA;HPA3;PPP1R93;GPalpha Iib;Integrin alpha-Iib;Platelet membrane glycoprotein Iib;ITGAB; &alpha-IIb integrin-n;BDPLT16;alpha 2b (platelet glycoprotein IIb of IIb/IIIa complex;alpha subunit;antigen CD41;antigen CD41);form 2;Integrin;Integrin alpha 2b;Integrin alpha IIb;Integrin alpha-IIb light chain;integrin αⅡbβ3;ITA2B;platelet fibrinogen receptor;platelet glycoprotein IIb of IIb/IIIa complex;platelet specific antigen BAK
Area di ricerca:Cardiovascular;Immunology;Signal Transduction;Stem Cells
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