CD38, also known as ADP-ribosyl cyclase, is a Type II integral membrane protein. The enzyme is able to transform NAD(P)+ into three different products with calcium mobilizing ability, cyclic ADP-ribose, NAADP+, and ADP-ribose . CD38 is expressed in B and T lymphocytes, osteoclasts, and in cardiac, pancreatic, liver and kidney cells . Through its production of cyclic ADP-ribose, CD38 modulates calcium-mediated signal transduction in many types of cells, including neutrophils and pancreatic beta cells.

Dettagli prodotto

• Codice: AN003490P_25mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: HB-7
• Applicazione: FCM
• Simbolo target: cADPr hydrolase;ADP-ribosyl cyclase;cyclic ADP-ribose hydrolase;Acute lymphoblastic leukemia cells antigen CD;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase;CD38;ADPRC 1;ADPRC1;Acute lymphoblastic leukemia cells antigen CD38;ADP ribosyl cyclase;ADP-ribosyl cyclase 1;ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1;cADPr hydrolase 1;CD38 antigen;CD38 molecule;CD38H;Cyclic ADP ribose hydrolase;EC 3.2.2.5;I-19;NIMR5 antigen;p45;ADP-ribosyl;T10;cyclase;2'-phospho-ADP-ribosyl cyclase;2'-phospho-ADP-ribosyl cyclase/2'-phospho-cyclic-ADP-ribose transferase;2'-phospho-cyclic-ADP-ribose transferase;ADP-ribosyl cyclase 1 (ADPRC 1);Cyclic ADP-ribose hydrolase 1 (cADPr hydrolase 1);cyclic ADP-ribose hydrolase 1; ADP-ribosyl cyclase;ADP ribosyl cyclase;ADPRC1;CD38 antigen;CD38 molecule;CD38H;Cyclic ADP ribose hydrolase;EC 3.2.2.5;I-19;NIMR5 antigen;p45;T10;Acute lymphoblastic leukemia cells antigen CD38; ADP ribosyl cyclase; ADPRC1; CD38 antigen; CD38 molecule; CD38H; Cyclic ADP ribose hydrolase; EC 3.2.2.5; I-19; NIMR5 antigen; p45; T10;ADP ribosyl cyclase 1;ADP ribosyl cyclase/cyclic ADP-ribose hydrolase;CD 38;CD38 antigen (p45);Cd38-rs1;Cyclic ADP ribose hydrolase 1;Ecto nicotinamide adenine dinucleotide glycohydrolase;I19 (mouse);Lymphocyte differentiation antigen CD38;NAD(+) nucleosidase;NIM-R5 antigen;NIMR5 antigen (mouse);OTTHUMP00000158633;OTTHUMP00000217743
• Area di ricerca: Immunology;Stem Cells;Cancer;Metabolism