CD52, also known as Cambridge pathology antigen 1 (CAMPATH-1), is a 25-29 kD glycoprotein containing a large N-linked carbohydrate moiety. The actual molecule of CD52 is only 8-9 kD. It is expressed in the male reproductive tract and on virtually all lymphocytes (T and B cells), as well as macrophages/monocytes, eosinophils, and red cells. CD52 is thought to play a role in carrying and orienting carbohydrates. CD52 is a potent target for complement-mediated lysis and antibody-mediated cellular cytotoxicity and has been used as a depletion target for chronic lymphocytic leukemia (CLL)/lymphoma and immunosuppression.
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Isotipo: Rabbit IgG, κ
Clonalità: Monoclonal
Clone: Campath-1G
Applicazione: FCM
Simbolo target: CDW;Epididymal secretory protein E;Human epididymis-specific protein;CAMPATH;CAMPATH-1;CAMPATH-1 antigen;CD52 antigen;CD52 molecule;Epididymal secretory protein E5;HEL-S-171mP;Human epididymis-specific protein 5;CDW52;HE5;CD52; HE5
Area di ricerca:Immunology
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