CD40 is a type I transmembrane glycoprotein belonging to the TNF receptor superfamily. The mature hCD40 consists of a 172 amino acid (aa) extracellular domain, a 22 aa transmembrane region and a 62 aa cytoplasmic domain . Human and mouse CD40 share 62% aa identity. CD40 is expressed in B cells, follicular dendritic cells, dendritic cells, activated monocytes, macrophages, endothelial cells, vascular smooth muscle cells, and several tumor cell lines.
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Isotipo: Mouse IgG2b, κ
Clonalità: Monoclonal
Clone: 3A8
Applicazione: FCM
Simbolo target: CDW;B-cell surface antigen CD;Tumor necrosis factor receptor superfamily member;TNFRSF;CD40;Bp50;CDW40;TNFRSF5;p50;Tumor necrosis factor receptor superfamily member 5;B-cell surface antigen CD40;CD40L receptor; TNFRSF5;AI326936;B cell associated molecule CD40;B cell surface antigen CD40;B cell-associated molecule;CD 40;CD40 (protein);CD40 antigen;CD40 antigen (TNF receptor superfamily member 5);CD40 molecule;CD40 protein;CD40 type II isoform;GP39;HIGM1;IGM;IMD3;isoform CRA_a;member 5;MGC9013;Nerve growth factor receptor related B lymphocyte activation molecule;OTTHUMP00000031699;OTTHUMP00000031700;TBAM;T-BAM;TNF receptor superfamily member 5;TNR5;TRAP;Tumor necrosis factor receptor superfamily;Tumor necrosis factor receptor superfamily member 5 precursor
Area di ricerca:Immunology;Cardiovascular;Stem Cells
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