CD11a is a 170-180 kD type I transmembrane glycoprotein also known as LFA-1α chain and integrin αL subunit. CD11a non-covalently associates with integrin β2 (CD18) to form LFA-1. It is expressed on all leukocytes, including B and T lymphocytes, monocytes, macrophages, neutrophils, basophils and eosinophils. It is absent on non-hematopoietic tissues and platelets. CD11a plays a central role in leukocyte cell-cell interactions and is important in lymphocyte costimulation. CD11a/CD18 binds to ICAM-1 (CD54), ICAM-2 (CD102), and ICAM-3 (CD50).

Codice: E-AB-F1055A_50mg | Marca: Elabscience | Confezionamento: 50mg

Specie: HumanIsotipo: Mouse IgG1, κClone: TS1/22.1.1.13
Dettagli prodotto
  • Codice: E-AB-F1055A_50mg
  • Marca: Elabscience
  • Specie target: Human
  • Host: Mouse
  • Concentrazione: ≥ 1 mg/mL
  • Link: Apri link
  • Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
  • Isotipo: Mouse IgG1, κ
  • Clonalità: Monoclonal
  • Clone: TS1/22.1.1.13
  • Applicazione: FCM
  • Simbolo target: CD11 antigen-like family member A;CD11a;Integrin alpha-L;Itgal;LFA-1A;Ly-15;Lymphocyte antigen 15
  • Area di ricerca: Cell Adhesion;Cell Biology;Costimulatory Molecules;Immunology;Innate Immunity;Neuroinflammation;Neuroscience