CD32 is a 40 kD polymorphic transmembrane glycoprotein also known as FcγRII and FCRII. It is an immunoglobulin superfamily member expressed on monocytes/macrophages, granulocytes, platelets and B cells. There are at least 6 isoforms of CD32 resulting from alternative mRNA splicing. CD32 mediates phagocytosis and oxidative burst in granulocytes, as well as platelet aggregation and immunomodulation. The extracellular domain of CD32 binds to polymeric and aggregated IgG and immune complexes, while the intracellular domain has been reported to associate with SHP-1 (B1 isoform).

Codice: E-AB-F1075A_25mg | Marca: Elabscience | Confezionamento: 25mg

Specie: HumanIsotipo: Mouse IgG2b, κClone: IV-3

Recombinant Human CD32 protein

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Codice: E-AB-F1075A_25mg
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotipo: Mouse IgG2b, κ
Clonalità: Monoclonal
Clone: IV-3
Applicazione: FCM;Block
Simbolo target: IGFR2;CD32;CDw32;FCG2;FCGR2B;Fc-gamma RII-b;Fc-gamma-RIIb;FcRII-b;IgG Fc receptor II-b;Low affinity immunoglobulin gamma Fc region receptor II-b
Area di ricerca: Immunology;Innate Immunity

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