CD117 is a 145 kD immunoglobulin superfamily member also known as c-Kit and stem cell factor receptor (SCFR). It is a transmembrane tyrosine-kinase receptor that binds the c-Kit ligand (also known as steel factor, stem cell factor, and mast cell growth factor). CD117 is expressed on hematopoietic stem cells (including multipotent hematopoietic stem cells, progenitors committed to myeloid and/or erythroid lineages, and T and B cell precursors), mast cells, and acute myeloid leukemia (AML) cells. CD117 interaction with its ligand is critical for the development of hematopoietic stem cells.

Codice: E-AB-F10920_1mg | Marca: Elabscience | Confezionamento: 1mg

Specie: MouseIsotipo: Rat IgG2b, κClone: 2B8

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Codice: E-AB-F10920_1mg
Marca: Elabscience
Specie target: Mouse
Host: Rat
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Isotipo: Rat IgG2b, κ
Clonalità: Monoclonal
Clone: 2B8
Applicazione: FCM
Simbolo target: CD117;Kit;Mast/stem cell growth factor receptor Kit;Proto-oncogene c-Kit;SCFR;Tyrosine-protein kinase Kit
Area di ricerca: Immunology;Stem Cells

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