CD45RO is a 180 kD single chain membrane glycoprotein. It is a splice variant of tyrosine phosphatase CD45, lacking the A, B, and C determinants. The CD45RO isoform is expressed on activated and memory T cells, some B cell subsets, activated monocytes/macrophages, and granulocytes. CD45RO enhances both T cell receptor and B cell receptor signaling mediated activation. CD45 and its isoforms non-covalently associate with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1 and CD22. CD45 isoform expression can change in response to cytokines.

Codice: E-AB-F1139A_5mg | Marca: Elabscience | Confezionamento: 5mg

Specie: HumanIsotipo: Mouse IgG2a, κClone: UCHL1

Recombinant Human CD45RO protein

Torna alla lista Apri link

Codice: E-AB-F1139A_5mg
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Isotipo: Mouse IgG2a, κ
Clonalità: Monoclonal
Clone: UCHL1
Applicazione: FCM
Area di ricerca: Cell Biology;Immunology;Inhibitory Molecules;Neuroscience;Neuroscience Cell Markers;Stem Cells

Scheda prodotto