The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor has been shown to activate NF-kappaB through its interaction with adaptor proteins TRAF2 and TRAF5. Knockout studies in mice suggested that this receptor promotes the expression of apoptosis inhibitors BCL2 and BCL2lL1/BCL2-XL, and thus suppresses apoptosis. The knockout studies also suggested the roles of this receptor in CD4+ T cell response, as well as in T cell-dependent B cell prolifeRation and differentiation.

Dettagli prodotto

• Codice: E-AB-F1153A_100μg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1,κ
• Clonalità: Monoclonal
• Clone: Ber-ACT35
• Applicazione: FCM
• Simbolo target: IMD;ACT;Tumor necrosis factor receptor superfamily member;Txgp;TNFRSF;TNFRSF4;ACT35;CD134;IMD16;OX40;TXGP1L;ACT35 antigen;OX40L receptor;Recombinant Human OX40/TNFRSF4 Protein (C-Fc);Recombinant Human OX40/TNFRSF4 Protein (C-Fc-Avi);Recombinant Human OX40/TNFRSF4 Protein (C-mFc);Recombinant Human OX40/TNFRSF4 Protein (N-Fc);Tumor necrosis factor receptor superfamily member 4;Txgp1;OX-40; TNFRSF4;Recombinant Human OX40/TNFRSF4 Protein (C-Fc);Recombinant Human OX40/TNFRSF4 Protein (N-Fc)
• Area di ricerca: Immunology;Stem Cells