This gene encodes a CXC chemokine receptor specific for stromal cell-derived factor-1. The protein has 7 transmembrane regions and is located on the cell surface. It acts with the CD4 protein to support HIV entry into cells and is also highly expressed in breast cancer cells. Mutations in this gene have been associated with WHIM (warts, hypogammaglobulinemia, infections, and myelokathexis) syndrome. Alternate transcriptional splice variants, encoding different isoforms, have been characterized.

Dettagli prodotto

• Codice: E-AB-F11570_25mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
• Isotipo: Mouse IgG2a, κ
• Clonalità: Monoclonal
• Clone: 12G5
• Applicazione: FCM
• Simbolo target: LCR;CXCR;C-X-C chemokine receptor type;LAP;CD184;D2S201E;FB22;HM89;HSY3RR;LAP-3;LAP3;LCR1;LESTR;NPY3R;NPYR;NPYRL;NPYY3R;WHIM;WHIMS;CXCR4;C-X-C chemokine receptor type 4;Fusin;SDF 1 receptor; Fusin; LESTR;CD184 antigen;Chemokine (C X C motif) receptor 4;Chemokine CXC Motif Receptor 4;C-X-C motif chemokine receptor 4;CXCR-4;CXC-R4;LAP 3;Leukocyte derived seven transmembrane domain receptor;Leukocyte-derived seven transmembrane domain receptor;Lipopolysaccharide associated protein 3;Neuropeptide Y receptor Y3;NPYY3;Probable G protein coupled receptor lcr1 homolog;SDF-1 receptor;SEVEN-TRANSMEMBRANE-SEGMENT RECEPTOR;Stromal cell derived factor 1 receptor;Stromal cell-derived factor 1 receptor
• Area di ricerca: Immunology;Microbiology;Neuroscience;Stem Cells;Cancer;Metabolism