Endoglin (ENG, CD105) is a homodimeric cell membrane glycoprotein of 180 kDa, composed of disulphide-linked subunits of 90-95 kDa. Endoglin is a proliferation-associated and hypoxia-inducible protein mainly expressed on vascular endothelial cells. It acts as an accessory receptor for transforming growth factor beta (TFG-β) and is involved in vascular development and remodelling. The important role of Endoglin in angiogenesis and in tumor progression makes it an ideal target for antiangiogenic therapy and a good marker for tumor prognosis.

Codice: E-AB-F12330_1mg | Marca: Elabscience | Confezionamento: 1mg

Specie: MouseIsotipo: Rat IgG2a, κClone: MJ7/18

Recombinant Human CD105 protein

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Codice: E-AB-F12330_1mg
Marca: Elabscience
Specie target: Mouse
Host: Rat
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotipo: Rat IgG2a, κ
Clonalità: Monoclonal
Clone: MJ7/18
Applicazione: FCM
Simbolo target: HHT;ORW1;AI528660;AI662476;CD105;END;Endo;Endoglin;HHT1;ORW;S-endoglin;Edg;Eng;END;HHT1;ORW;ORW1;CD 105;CD105 antigen;EGLN;FLJ41744;Osler Rendu Weber syndrome 1;RP11 228B15.2;SN6

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