CD107a, also known as Lysosome-Associated Membrane Protein 1 (LAMP-1) or LGP-120, is a 110-140 kD type I membrane glycoprotein. Mature CD107a is heavily glycosylated from a 40 kD core protein. This molecule is located on the luminal side of lysosomes. Upon activation, CD107a is transferred to the cell membrane surface of activated platelets, activated lymphocytes, macrophages, epithelial cells, endothelial cells, and some tumor cells. CD107a has been suggested to play a role in the protection of lysosomal membrane from lysosomal hydrolases which is involved in cell adhesion and regulation of tumor metastasis, and mediates autoimmune disease progression. CD107a is a ligand for galaptin and E-selectin. Surface expression of LAMP-1 has been shown to correlate with CD8+ T cell and NK cell cytotoxicity.

Codice: E-AB-F1254A_100μg | Marca: Elabscience | Confezionamento: 100μg

Specie: MouseIsotipo: Rat IgG2a, κClone: 1D4B

Recombinant Mouse CD107a protein

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Codice: E-AB-F1254A_100μg
Marca: Elabscience
Specie target: Mouse
Host: Rat
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles. This preparation contains no preservatives, thus it should be handled under aseptic conditions.
Isotipo: Rat IgG2a, κ
Clonalità: Monoclonal
Clone: 1D4B
Applicazione: FCM
Simbolo target: LGP;lysosomal membrane glycoprotein;Lysosome-associated membrane glycoprotein;120 kDa lysosomal membrane glycoprotein;CD107 antigen-like family member A;CD107a;LGP-120;LGP-A;lysosomal membrane glycoprotein 1;Lysosomal membrane glycoprotein A;Lysosome-associated membrane glycoprotein 1;lysosome-associated membrane protein 1;P2B;Lamp-1;Lamp1; LGP-120

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