This gene encodes a pentaspan transmembrane glycoprotein. The protein localizes to membrane protrusions and is often expressed on adult stem cells, where it is thought to function in maintaining stem cell properties by suppressing differentiation. Mutations in this gene have been shown to result in retinitis pigmentosa and Stargardt disease. Expression of this gene is also associated with several types of cancer. This gene is expressed from at least five alternative promoters that are expressed in a tissue-dependent manner. Multiple transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: E-AB-F12680P_25μg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG1, κ
• Clonalità: Monoclonal
• Clone: W6B3C1
• Applicazione: FCM
• Simbolo target: PROM;CORD;MCDR;MSTP;STGD;PROML;PROM1;AC133;CD133;CORD12;MCDR2;MSTP061;PROML1;RP41;STGD4;Prominin-1; Prominin-1;AC133;CD133;CORD12;MCDR2;MSTP061;PROML1;RP41;STGD4;Antigen AC133;Hematopoietic stem cell antigen;hProminin;OTTHUMP00000217744;OTTHUMP00000217745;OTTHUMP00000217746;Prominin I;Prominin like 1;Prominin like protein 1 precursor;Prominin mouse like 1;Prominin1;Prominin-like protein 1
• Area di ricerca: Neuroscience;Stem Cells