The protein encoded by this gene is a member of the scavenger receptor cysteine-rich (SRCR) superfamily, and is exclusively expressed in monocytes and macrophages. It functions as an acute phase-regulated receptor involved in the clearance and endocytosis of hemoglobin/haptoglobin complexes by macrophages, and may thereby protect tissues from free hemoglobin-mediated oxidative damage. This protein may also function as an innate immune sensor for bacteria and inducer of local inflammation. Alternatively spliced transcript variants encoding different isoforms have been described for this gene.

Codice: E-AB-F12980P_100μg | Marca: Elabscience | Confezionamento: 100μg

Specie: HumanIsotipo: Mouse IgG1, κClone: GHI/61

Recombinant Human CD163 protein

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Codice: E-AB-F12980P_100μg
Marca: Elabscience
Specie target: Human
Host: Mouse
Concentrazione: ≥ 1 mg/mL
Link: Apri link
Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
Isotipo: Mouse IgG1, κ
Clonalità: Monoclonal
Clone: GHI/61
Applicazione: FCM
Simbolo target: GHI/;SCARI;CD163;M130;MM130;SCARI1;ED2(rat);GHI/61;Hemoglobin/Haptoglobin Complex Receptor;macrophage-associated antigen;p155;RM3/1; GHI/61
Area di ricerca: Immunology;Cardiovascular

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