IL-4 is a pleiotropic cytokine that is produced by activated T cells, mast cells and basophils. IL-4 elicits many different biological responses, but has two dominant functions. The first is regulating differentiation of naïve CD4+ T cell to the Th2 type. Th2 cells produce IL-4, IL-5, IL-10 and IL-13, which tend to favor a humoral immune response while suppressing a cell-mediated immune response controlled by Th1 cells. The second is regulating IgE and IgG1 production by B cells.

Dettagli prodotto

• Codice: E-AB-F13760P_1mg
• Marca: Elabscience
• Specie target: Rat
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG2a, κ
• Clonalità: Monoclonal
• Clone: 5B3
• Applicazione: FCM
• Simbolo target: Interleukin;B-cell growth factor;B-cell stimulatory factor;Lymphocyte stimulatory factor;BCGF1;B-cell IGG differentiation factor;B-cell stimulatory factor 1;BCGF-1;Binetrakin;BSF1;Interleukin-4;Lymphocyte stimulatory factor 1;Pitrakinra;Il4;BSF-1;Lymphocy;Il 4;B-cell growth factor 1;Il-4;IL4、BCGF-1、BCGF1、BSF-1、BSF1