This gene encodes an integrin beta chain, which combines with multiple different alpha chains to form different integrin heterodimers. Integrins are integral cell-surface proteins that participate in cell adhesion as well as cell-surface mediated signalling. The encoded protein plays an important role in immune response and defects in this gene cause leukocyte adhesion deficiency. Alternative splicing results in multiple transcript variants.

Dettagli prodotto

• Codice: E-AB-F14120P_50mg
• Marca: Elabscience
• Specie target: Human
• Host: Mouse
• Concentrazione: ≥ 1 mg/mL
• Link: Apri link
• Stoccaggio: Store at 4°C valid for 12 months or -20°C valid for long term storage, avoid freeze / thaw cycles.
• Isotipo: Mouse IgG2a, κ
• Clonalità: Monoclonal
• Clone: 60.3
• Applicazione: FCM
• Simbolo target: MAC;MFI;LFA;ITGB;Integrin beta;CD18;LAD;LCAMB;LFA-1;MAC-1;MF17;MFI7;ITGB2;Cell surface adhesion glycoproteins LFA-1/CR3/p150+95 subunit beta;Complement receptor C3 subunit beta;Integrin beta-2;&beta-2 integrin-n;95 subunit beta;959 beta subunit precursor);Beta 2 (antigen CD18 (p95);beta 2 (complement component 3 receptor 3 and 4 subunit);CD 18;CD18/11B;CD18/11C;Cell surface adhesion glycoprotein LFA 1/CR3/P150;Cell surface adhesion glycoproteins LFA 1/CR3/p150;Cell surface adhesion glycoproteins LFA-1/CR3/p150;Complement component 3 receptor 3 and 4 subunit;Complement receptor C3 beta subunit;Integrin;Integrin beta 2;Integrin beta chain beta 2;Integrin beta-2 (ITGB2);ITB2;Leukocyte associated antigens CD18/11A;Leukocyte cell adhesion molecule CD18;LFA 1;LFA1;Lymphocyte function associated antigen 1;Lymphocyte function associated antigen 1 (LFA1);MAC 1;MAC1;Macrophage antigen 1 (mac1) beta;OTTHUMP00000115278;OTTHUMP00000115279;OTTHUMP00000115280;OTTHUMP00000115281;OTTHUMP00000115282
• Area di ricerca: Signal Transduction;Immunology;Stem Cells