On ligand binding, forms a receptor complex consisting of two type II and two type I transmembrane serine/threonine kinases. Type II receptors phosphorylate and activate type I receptors which autophosphorylate, then bind and activate SMAD transcriptional regulators. Receptor for TGF-beta.

Dettagli prodotto

• Codice: PDEB100010_1mg
• Marca: Elabscience
• Specie target: Bovine
• Host: E.coli
• Confezionamento: Lyophilized from sterile PBS, pH 7.4.<br/>Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: TGFBR1
• Ig target: AAT5;ACVRLK 4;ALK 5;Activin A receptor type II like kinase 53kDa;Activin receptor like kinase 5;LDS1A;MSSE;SKR4;Serine/threonine-protein kinase receptor R4;TGF beta Receptor I;TGFR 1;TbetaR-I
• Area di ricerca: Cardiovascular;Signal Transduction;Stem Cells;Cancer;Metabolism;Neuroscience