Involved in the activation cascade of caspases responsible for apoptosis execution. Binding of caspase-9 to Apaf-1 leads to activation of the protease which then cleaves and activates effector caspases caspase-3 (CASP3) or caspase-7 (CASP7). Promotes DNA damage-induced apoptosis in a ABL1/c-Abl-dependent manner. Proteolytically cleaves poly(ADP-ribose) polymerase (PARP).

Dettagli prodotto

• Codice: PDEH100514_100μg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: CASP9
• Ig target: MCH;Apoptotic protease Mch;PPP1R;ICE-LAP;CASP9;APAF-3;APAF3;ICE-LAP6;MCH6;PPP1R56;caspase-9;Caspase 9;CASP-9;Apoptotic protease Mch-6;Apoptotic protease-activating factor 3 (APAF-3);ICE-like apoptotic protease 6 (ICE-LAP6);Apoptosis related cysteine peptidase;Apoptotic protease-activating factor 3;Caspase 9 apoptosis related cysteine peptidase;Caspase 9 Dominant Negative;Caspase 9c;Caspase-9 subunit p10;ICE LAP6;ICE like apoptotic protease 6;ICE-like apoptotic protease 6;protein phosphatase 1;regulatory subunit 56;RNCASP9