This gene is one of several CC cytokine genes clustered on the p-arm of chromosome 9. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. The protein encoded by this gene is chemotactic for skin-associated memory T lymphocytes. This cytokine may also play a role in mediating homing of lymphocytes to cutaneous sites. It specifically binds to chemokine receptor 10 (CCR10). Studies of a similar murine protein indicate that these protein-receptor interactions have a pivotal role in T cell-mediated skin inflammation.

Dettagli prodotto

• Codice: PDEH100528_20μg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: CCL27
• Ig target: ALP;C-C motif chemokine 27;CC chemokine ILC;Ccl27;CCL27;Chemokine (C-C motif) ligand 27;CTACK;CTAK;Cutaneous T cell attracting chemokine;Cutaneous T-cell-attracting chemokine;ESkine;IL 11 R alpha locus chemokine;IL-11 R-alpha-locus chemokine;ILC;PESKY;SCYA27;Skinkine;Small inducible cytokine A27;small inducible cytokine subfamily A (Cys-Cys);member 27;Small-inducible cytokine A27
• Area di ricerca: Cancer;Immunology