CCL14a/HCC-1 has an important biological role in other mammals by evolving under positive selection that has been lost in Ochotonidae (subgenera Pika and Lagotona). CC chemokine ligand 14, CCL14a/HCC-1, is a human CC chemokine that is of recent interest because of its natural ability, upon proteolytic processing of the first eight NH2-terminal residues, to bind to and signal throμgh the human immunodeficiency virus type-1 (HIV-1) co-receptor, CC chemokine receptor 5 (CCR5). Embryo implantation is a complex process involving blastocyst attachment to the endometrial epithelium and subsequent trophoblast invasion of the decidua. We have previously shown that the chemokines CX3CL1 and CCL14a/HCC-1 are abundant in endometrial vasculature, epithelial, and decidual cells at this time, and that their receptors, CX3CR1 and CCR1, are present on invading human trophoblasts. CX3CL1 and CCL14a/HCC-1 promote trophoblast migration.

Codice: PDEH100598_20μg | Marca: Elabscience | Confezionamento: 20μg

Specie: Human

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Codice: PDEH100598_20μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Link: Apri link
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: CCL14a/HCC-1
Ig target: CCL;HCC-1/HCC;SCYA;Chemokine CC-1/CC;C-C motif chemokine 14;CC-1;CC-3;Chemokine CC-1/CC-3;HCC-1;HCC-1(1-74);HCC-1/HCC-3;HCC-3;NCC-2;Small-inducible cytokine A14;NCC2;SCYA14;CCL14;CKb1;MCIF;SCYL2
Area di ricerca: Immunology;Signal Transduction;Metabolism

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