Cardiotrophin-like cytokine (CLC), also referred to as novel neurotrophin-1 (NNT-1) or B cell-stimulating factor-3 (BSF-3), is a new member of the IL-6 family of structurally related cytokines that includes IL-6, CNTF, LIF, CT-1, IL-11 and OSM. All family members share the receptor subunit gp130 that belong to the type I cytokine receptor superfamily. Ligand binding leads to gp130 homodimerization or heterodimerization (with LIF receptor or OSM receptor beta ), and induces cell signaling and functional activity. For several family members, including CNTF, IL-6, and IL-11, binding of the ligand to a specific receptor alpha subunit (CNTF R alpha, IL-6 R alpha, or IL-11 R alpha ) is required prior to gp130 homo- or hetero-dimerization.

Codice: PDEH100645_100μg | Marca: Elabscience | Confezionamento: 100μg

Specie: Human

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Codice: PDEH100645_100μg
Marca: Elabscience
Specie target: Human
Host: E.coli
Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Link: Apri link
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: CLC
Ig target: LGALS;Galectin;Gal;CLC;GAL10;Gal-10;LGALS10;LGALS10A;LPPL_HUMAN;Charcot Leyden crystal protein;Eosinophil lysophospholipase;Gal 10;Galectin 10;Lysolecithin acylhydrolase;Charcot-Leyden crystal protein (CLC);Galectin-10
Area di ricerca: Immunology;Signal Transduction

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