This gene encodes the human homolog of the proto-oncogene c-kit. C-kit was first identified as the cellular homolog of the feline sarcoma viral oncogene v-kit. This protein is a type 3 transmembrane receptor for MGF (mast cell growth factor, also known as stem cell factor). Mutations in this gene are associated with gastrointestinal stromal tumors, mast cell disease, acute myelogenous lukemia, and piebaldism. Multiple transcript variants encoding different isoforms have been found for this gene.

Dettagli prodotto

• Codice: PDEH100679_1mg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Lyophilized from sterile PBS, pH 7.4.<br/>Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: KIT;SCFR
• Ig target: C Kit;CD117;KIT;KIT oncogene;KIT proto oncogene receptor tyrosine kinase;Kit;Kit Ligand;MGF;Mast cell growth factor receptor;Mast/stem cell growth factor receptor Kit;PBT;Piebald trait protein;Proto oncog;Proto oncogene c Kit;c-Kit;c-Kit Ligand;p145 c-kit
• Area di ricerca: Immunology Tags & Cell Markers Signal Transduction Neuroscience Stem Cells Cancer Developmental Biology