Essential mediator of p53/TP53-dependent and p53/TP53-independent apoptosis . Functions by promoting partial unfolding of BCL2L1 and dissociation of BCL2L1 from p53/TP53. Regulates ER stress-induced neuronal apoptosis.
Confezionamento: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% Tween 80.<br/>Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Applicazione: Immunogen
Simbolo target: PUMA;BBC3
Ig target: BBC 3;BBC3_HUMAN;BCL 2 binding component 3;BCL2 binding component 3;Bbc3;Bcl-2-binding component 3;JFY 1;JFY-1;JFY1;PUMA alpha;PUMA/JFY1;p53 Upregulated Modulator of Apoptosis;p53 up regulated modulator of apoptosis;p53 up-regulated modulator of apoptosis
Area di ricerca:Cell BiologySignal TransductionCancerMetabolism
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