Inhibits the activity of interleukin-1 by binding to receptor IL1R1 and preventing its association with the coreceptor IL1RAP for signaling. Has no interleukin-1 like activity. Binds functional interleukin-1 receptor IL1R1 with greater affinity than decoy receptor IL1R2, however, the physiological relevance of the latter association is unsure.

Dettagli prodotto

• Codice: PDEH100726_1mg
• Marca: Elabscience
• Specie target: Human
• Host: E.coli
• Confezionamento: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% Tween 80.<br/>Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: IL-1Ra
• Ig target: IL1F;MVCD;IL1RN;DIRA;ICIL-1RA;IL-1RN;IL-1ra;IL-1ra3;IL1F3;IL1RA;IRAP;MVCD4;Anakinra;IL1 inhibitor;Interleukin-1 receptor antagonist protein;F630041P17Rik;ICIL 1RA;ICIL1RA;IL1RN (IL1F3);Interleukin 1 receptor antagonist;Intracellular IL 1 receptor antagonist type II;Intracellular interleukin 1 receptor antagonist (icIL 1ra);MGC10430;Type II interleukin 1 receptor antagonist
• Area di ricerca: Cancer;Cardiovascular;Immunology;