Adapter protein which binds ubiquitin and may regulate the activation of NFKB1 by TNF-alpha, nerve growth factor (NGF) and interleukin-1. May play a role in titin/TTN downstream signaling in muscle cells. May regulate signaling cascades through ubiquitination. Adapter that mediates the interaction between TRAF6 and CYLD (By similarity). May be involved in cell differentiation, apoptosis, immune response and regulation of K(+) channels.
Confezionamento: Lyophilized from sterile PBS, pH 7.4.<br/>Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: SQSTM1;p62
Ig target: A170;DMRV;EBI 3 associated protein p60;EBIAP;FTDALS3;ORCA;OSF-6;OSIL;P62b;PDB 3;PDB3;SQSTM 1;STAP;STONE14;Sequestosome 1;ZIP3;p60
Area di ricerca:Signal Transduction;Epigenetics and Nuclear Signaling;Cardiovascular;Cancer;Neuroscience
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