CCL24, also known as Eotaxin-2 and MPIF-2, belongs to the intercrine beta (chemokine CC) family. CCL24 gene belongs to the subfamily of small cytokine CC genes. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The CC cytokines are proteins characterized by two adjacent cysteines. CCL24 displays chemotactic activity on resting T lymphocytes, a minimal activity on neutrophils, and is negative on monocytes and activated T lymphocytes. CCL24 is also a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. CCL24 is chemotactic for resting T-lymphocytes, and eosinophils. It has lower chemotactic activity for neutrophils but none for monocytes and activated lymphocytes. It is a strong suppressor of colony formation by a multipotential hematopoietic progenitor cell line. Eotaxin-2 interacts with an chemokine receptor CCR3 to induce chemotaxis in eosinophils. Elevated level of Eotaxin-2 has been seen in patients with an aspirin-exacerbated respiratory disease.

Codice: PDEM100130_1mg | Marca: Elabscience | Confezionamento: 1mg

Specie: Mouse

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Codice: PDEM100130_1mg
Marca: Elabscience
Specie target: Mouse
Host: E.coli
Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Link: Apri link
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: Ccl24
Ig target: C-C motif chemokine 24;CCL24;CCL24;Chemokine CC Motif Ligand 24;CK beta 6;CK-beta-6;Ckb6;Eosinophil chemotactic protein 2;Eotaxin-2;MPIF-2;MPIF2;Myeloid progenitor inhibitory factor 2;SCYA24;Small inducible cytokine subfamily A (Cys-Cys) member 24;Small-inducible cytokine A24
Area di ricerca: Immunology

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