ADAM8, also known as cell surface antigen MS2 or CD156a, is a member of the ADAM family that contains a disintegrin and metalloprotease-like domain. ADAM8 can cleave a variety of substrates and has been shown as a sheddase for the low affinity IgE receptor CD23 and the neural recognition molecule CHL1. Expression and regulation studies suggest that ADAM8 is a novel osteoclast stimulating factor and may play a role in asthma. It can be activated and assayed under the conditions described in the Activity Assay Protocol.
Confezionamento: Lyophilized from sterile PBS, pH 7.4.<br/>Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.<br/>Please refer to the specific buffer information in the printed manual.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: ADAM8;CD156a
Ig target: ADAM 8;CD antigen CD156a;Cell surface antigen MS2;Disintegrin and metalloproteinase domain-containing protein 8;EC 3.4.24.;MS2
Area di ricerca:Cell biology
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