Serine protease that degrades elastin, fibronectin, laminin, vitronectin, and collagen types I, III, and IV (in vitro. By cleaving and activating receptor F2RL1/PAR-2, enhances endothelial cell barrier function and thus vascular integrity during neutrophil transendothelial migration. May play a role in neutrophil transendothelial migration, probably when associated with CD177.

Dettagli prodotto

• Codice: PDMH100183_500μg
• Marca: Elabscience
• Specie target: Human
• Host: stable cell line
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: PRTN3
• Ig target: ACPA;AGP 7;AGP7;AGP7 serine proteinase;Azurophil Granule Protein 7;C ANCA;C ANCA antigen;C-ANCA antigen;CANCA;EC 3.4.21.76;Leukocyte proteinase 3;MBN;MBT;MBT WEGENER AUTOANTIGEN;Myeloblastin;Neutrophil proteinase 4;NP 4;NP-4;NP4;P29;PR 3;PR-3;PR3;Proteinase 3