This gene encodes a cytokine that acts as a growth and differentiation factor for both B cells and eosinophils. The encoded cytokine plays a major role in the regulation of eosinophil formation, maturation, recruitment and survival. The increased production of this cytokine may be related to pathogenesis of eosinophil-dependent inflammatory diseases. This cytokine functions by binding to its receptor, which is a heterodimer, whose beta subunit is shared with an the receptors for interleukine 3 (IL3) and colony stimulating factor 2 (CSF2/GM-CSF). This gene is located on chromosome 5 with anin a cytokine gene cluster which includes interleukin 4 (IL4), interleukin 13 (IL13), and CSF2 . This gene, IL4, and IL13 may be regulated coordinately by long-range regulatory elements spread over 120 kilobases on chromosome 5q31.

Codice: PDMH100203_1mg | Marca: Elabscience | Confezionamento: 1mg

Specie: Human

Torna alla lista Apri link

Codice: PDMH100203_1mg
Marca: Elabscience
Specie target: Human
Host: Mammalian
Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Link: Apri link
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: IL5
Ig target: B-cell differentiation factor I;Colony stimulating factor;EDF;Eosinophil differentiation factor;IL-5;IL5;IL5;Interleukin 5 (colony stimulating factor;eosinophil);Interleukin 5;Interleukin-5;T Cell Replacing Factor;T-cell replacing factor;TRF
Area di ricerca: Cancer;Immunology

Scheda prodotto