The CRTAM gene is upregulated in CD4 (see MIM 186940)-positive and CD8 (see CD8A, MIM 186910)-positive T cells and encodes a type I transmembrane protein with V and C1-like Ig domains. Interaction with CADM1 promotes natural killer (NK) cell cytotoxicity and interferon-gamma (IFN-gamma) secretion by CD8+ cells in vitro as well as NK cell-mediated rejection of tumors expressing CADM3 in vivo.

Dettagli prodotto

• Codice: PDMH100222_100μg
• Marca: Elabscience
• Specie target: Human
• Host: Mammalian
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: CRTAM
• Ig target: CD355;Class I MHC restricted T cell associated molecule;Class-I MHC-restricted T-cell-associated molecule;CRTAM;CRTAM;Cytotoxic and regulatory T cell molecule;Cytotoxic and regulatory T-cell molecule
• Area di ricerca: Immunology