The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor is expressed by activated, but not by resting, T and B cells. TRAF2 and TRAF5 can interact with an this receptor, and mediate the signal transduction that leads to the activation of NF-kappaB. This receptor is a positive regulator of apoptosis, and also has been shown to limit the proliferative potential of autoreactive CD8 effector T cells and protect the body against autoimmunity. Two alternatively spliced transcript variants of this gene encoding distinct isoforms have been reported.

Dettagli prodotto

• Codice: PDMH100233_1mg
• Marca: Elabscience
• Specie target: Human
• Host: Mammalian
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: CD30
• Ig target: CD 30;CD30;CD30 antigen;CD30L receptor;Cytokine receptor CD30;D1S166E;KI 1;KI 1 antigen;Ki-1 antigen;KI1;Lymphocyte activation antigen CD30;TNFRSF 8;Tnfrsf8;TNR8;Tumor necrosis factor receptor superfamily member 8
• Area di ricerca: Cancer;Immunology