Ptx3, also known as tumor necrosis factor-stimulated gene sequence-14 (TSG14), is a secreted pattern-recognition receptor that has a non-redundant role in resistance to selected microbial agents. Ptx3 belongs to the family of “long pentraxins”, which have C-terminal pentraxin domains and novel amino-terminal domains. Ptx3 binds selected pathogens, including Aspergillus fumigatus, Pseudomonas aeruginosa and Salmonella typhimurium. It is synthesized in IgA glomerulonephritis and activates mesangial cells.
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: PTX3
Ig target: AI607804;Pentaxin 3;Pentaxin-related protein PTX3;Pentraxin 3 long;Pentraxin-related gene;Pentraxin-related gene rapidly induced by IL-1 beta;Pentraxin-related protein PTX3;PTX3;PTX3;TNF alpha-induced protein 5;TNFAIP5;TSG-14;TSG14;Tumor necrosis factor alpha-induced protein 5;Tumor necrosis factor-inducible gene 14 protein;Tumor necrosis factor-inducible protein TSG-14
Area di ricerca:Cancer;Cardiovascular;Immunology
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