This gene encodes a cell surface adhesion molecule that belongs to a family of adhesion/homing receptors. The encoded protein contains a C-type lectin-like domain, a calcium-binding epidermal growth factor-like domain, and two short complement-like repeats. The gene product is required for binding and subsequent rolling of leucocytes on endothelial cells, facilitating their migration into secondary lymphoid organs and inflammation sites. Single-nucleotide polymorphisms in this gene have been associated with an various diseases including immunoglobulin A nephropathy. Alternatively spliced transcript variants have been found for this gene.

Dettagli prodotto

• Codice: PDMH100243_1mg
• Marca: Elabscience
• Specie target: Human
• Host: Mammalian
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: SELL
• Ig target: A.11;AI528707;CD62 antigen ligand;CD62 antigen-like family member L;CD62L;gp90-MEL;IgA nephropathy;susceptibility to;included;L Selectin;L-selectin;LAM-1;LAM1;LECAM1;LEU8;Leukocyte adhesion molecule 1;Leukocyte surface antigen Leu-8;Leukocyte-endothelial cell adhesion molecule 1;Lnhr;LSEL;Ly-22;Ly-m22;Lyam-1;LYAM1;LYAM1;Lymph node homing receptor;Lymphocyte adhesion molecule 1;Lymphocyte antigen 22;Lymphocyte surface MEL-14 antigen;MEL-14;Pln homing receptor;PLNHR;Selectin L;Selectin;lymphocyte;SELL;TQ1
• Area di ricerca: Cancer;Cardiovascular;Immunology;Stem Cells