The interleukin 2 (IL2) receptor alpha (IL2RA) and beta (IL2RB) chains, together with an the common gamma chain (IL2RG), constitute the high-affinity IL2 receptor. Homodimeric alpha chains (IL2RA) result in low-affinity receptor, while homodimeric beta (IL2RB) chains produce a medium-affinity receptor. Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolyisis. Alternately-spliced IL2RA mRNAs have been isolated, but the significance of each is presently unknown. Mutations in this gene are associated with an interleukin 2 receptor alpha deficiency.

Dettagli prodotto

• Codice: PDMH100268_20μg
• Marca: Elabscience
• Specie target: Human
• Host: Mammalian
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: IL2RA
• Ig target: Interleukin 2 receptor alpha chain;CD25;CD25 antigen;IDDM10;IL 2 receptor alpha subunit;IL-2 receptor subunit alpha;IL-2-RA;IL-2R subunit alpha;IL2 RA;IL2-RA;IL2R;IL2R;alpha chain;IL2RA;IL2RA;IMD41;Interleukin 2 receptor alpha;Interleukin 2 receptor;Interleukin-2 receptor subunit alpha;p55;t-cell growth factor receptor;TAC;TAC antigen;TCGFR
• Area di ricerca: Cancer;Immunology