DKK3 (dickkopf related protein 3) is a member of the dickkopf-related family consisting of DKK1 , DKK2 , DKK3 and DKK4. It is a secreted protein , and also known as REIC (Reduced Expansion in Immortalized Cells). The DKK3 protein is proposed to function as a secreted tumor suppressor since it is downregulated in a number of cancer cells and prostate cancer tissue and may be a promising candidate molecule for therapeutic interference. DKK3 protein is also a negative regulator of beta-catenin and its downregulation contribute to an activation of the beta-catenin signaling pathway.

Dettagli prodotto

• Codice: PDMH100318_1mg
• Marca: Elabscience
• Specie target: Human
• Host: Mammalian
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: DKK-3
• Ig target: UNQ;PRO;Dickkopf-Related Protein;hDkk;Dickkopf;DKK;DKK3;REIC;RIG;Dickkopf-3;Dickkopf-Related Protein 3;Dkk-3;hDkk-3;UNQ258;PRO295;Dickkopf 3;Dickkopf 3 homolog;Dickkopf 3 homolog (Xenopus laevis);Dickkopf homolog 3;Dickkopf related protein 3;Dickkopf related protein 3 Precursor;Dickkopf WNT signaling pathway inhibitor 3;Dickkopf3;DKK 3;hDkk 3;hDkk3;homolog of;Regulated in glioma;RIG-like 5-6;RIG-like 7-1;Xenopus
• Area di ricerca: Signal Transduction;Stem Cells