Neuropilins (NRPs) are single transmembrane receptors with short cytoplasmic tails and are dependent on receptors like VEGF receptors or Plexins for signal transduction. NRPs are known to be important in angiogenesis, lymphangiogenesis, and axon guidance. The Neuropilin-family consists of two members, Neuropilin-1 (NRP1) and Neuropilin-2 (NRP2). NRP2 is important for migration, antigen presentation, phagocytosis and cell-cell contact within the immune system. Additionally, posttranslational NRP2 modifications like polysialylation are crucial for the function of some immune cells.

Dettagli prodotto

• Codice: PDMH100445_500μg
• Marca: Elabscience
• Specie target: Human
• Host: Mammalian
• Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
• Link: Apri link
• Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
• Simbolo target: NRP2
• Ig target: PRO;NPN;NRP;neuropilin;vascular endothelial growth factor-165 receptor;VEGF165R;NRP2;NP2;NPN2;PRO2714;VEGF165R2;neuropilin-2;vascular endothelial growth factor-165 receptor 2;MGC126574;Neuropilin 2;Neuropilin2;NP 2;NPN 2;NRP 2;Receptor for VEGF165 and semaphorins class3;Vascular endothelial cell growth factor 165 receptor 2;Vascular endothelial growth factor 165 receptor 2;VEGF1265R2
• Area di ricerca: Cancer;Developmental Biology;Signal Transduction;Cardiovascular