LRG1 (Leucine-Rich Alpha-2-Glycoprotein 1) is a Protein Coding gene. LRG1 belongs to the leucine-rich repeat (LRR) family. Members of this family are involved in protein-protein interaction, signal transduction, and cell adhesion and development. LRG1 is expressed during granulocyte differentiation. It contains 4 LIM zinc-binding domains and 1 Rho-GAP domain. LRG1 is involved in promoting neovascularization (new blood vessel growth) by causing a switch in transforming growth factor-beta (TGFbeta) signaling in endothelial cells. LRG1 binds to the accessory receptor endoglin and promotes signaling via the ALK1-Smad1/5/8 pathway. It may be a potential therapeutic target for the treatment of diseases where there is aberrant neovascularization. Diseases associated with LRG1 include Appendicitis and Normal Pressure Hydrocephalus.

Codice: PDMH100450_20μg | Marca: Elabscience | Confezionamento: 20μg

Specie: Human

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Codice: PDMH100450_20μg
Marca: Elabscience
Specie target: Human
Host: Mammalian
Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Link: Apri link
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: LRG1
Ig target: HMFT;LRG1;HMFT1766;LRG;1300008B03Rik;2310031E04Rik;A2GL;Leucine rich alpha 2 glycoprotein;Leucine-rich alpha-2-glycoprotein;Leucine-rich alpha-2-glycoprotein 1;Leucine-rich alpha-2-glycoprotein precursor;leucine rich alpha-2-glycoprotein 1
Area di ricerca: Cancer;Neuroscience;Developmental Biology;Signal Transduction

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