P selectin (SELP) is a 140kDa protein that is stored in the alpha-granules of platelets and Weibel-Palade bodies of endothelial cells. SELP mediates rapid rolling of leukocyte rolling over vascular surfaces during the initial steps in inflammation through interaction with PSGL1. P selectin is a cell adhesion molecule on the surface of activated endothelial cells. Cellular adhesion molecules are a large family of proteins that attach the cytoskeleton and intracellular signaling cascades with the extracellular environment. SELP is a calcium-dependent receptor for myeloid cells that binds to sialylated forms of Lewis blood group carbohydrate antigens on neutrophils and monocytes. This protein redistributes to the plasma membrane during platelet activation and degranulation and mediates the interaction of activated endothelial cells or platelets with leukocytes.

Codice: PDMM100146_500μg | Marca: Elabscience | Confezionamento: 500μg

Specie: Mouse

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Codice: PDMM100146_500μg
Marca: Elabscience
Specie target: Mouse
Host: Mammalian
Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Link: Apri link
Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: P-Selectin/CD62P
Ig target: Granule membrane protein;Leukocyte-endothelial cell adhesion molecule;LECAM;CD62;CD62 antigen-like family member P;GMP140;GMP-140;Granule membrane protein 140;LECAM3;Leukocyte-endothelial cell adhesion molecule 3;PADGEM;PSEL;P-selectin;Grmp;Selp;CD62P; GMP-140; PADGEM

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