Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.

Codice: PDMR100100_20μg | Marca: Elabscience | Confezionamento: 20μg

Specie: Rat

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Codice: PDMR100100_20μg
Marca: Elabscience
Specie target: Rat
Host: Mammalian
Confezionamento: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
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Stoccaggio: Generally, lyophilized proteins are stable for up to 12 months when stored at -20 to -80℃. Reconstituted protein solution can be stored at 4-8℃ for 2-7 days. Aliquots of reconstituted samples are stable at < -20℃ for 3 months.
Simbolo target: IL-6
Ig target: Interleukin-6;B-cell stimulatory factor 2;IFN-β2
Area di ricerca: Immunology;Cell Biology;Signal Transduction

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